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Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.

Nucleotide excision repair (NER), one of the major cellular DNA repair systems, removes a wide range of lesions in a multi-enzyme reaction. In man, a NER defect due to a mutation in one of at least 11 distinct genes, can give rise to the inherited repair disorders xeroderma pigmentosum (XP), Cockayn...

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Foilsithe in:EMBO J
Main Authors: van Vuuren, A J, Appeldoorn, E, Odijk, H, Yasui, A, Jaspers, N G, Bootsma, D, Hoeijmakers, J H
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 1993
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8253091/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06044.x
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