Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.

Nucleotide excision repair (NER), one of the major cellular DNA repair systems, removes a wide range of lesions in a multi-enzyme reaction. In man, a NER defect due to a mutation in one of at least 11 distinct genes, can give rise to the inherited repair disorders xeroderma pigmentosum (XP), Cockayn...

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Detalhes bibliográficos
Main Authors: van Vuuren, A J, Appeldoorn, E, Odijk, H, Yasui, A, Jaspers, N G, Bootsma, D, Hoeijmakers, J H
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC413646/
https://ncbi.nlm.nih.gov/pubmed/8253091
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