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Intranasal Adenovirus-Vectored Vaccine for Induction of Long-Lasting Humoral Immunity-Mediated Broad Protection against Influenza in Mice

Influenza vaccines aimed at inducing antibody (Ab) responses against viral surface hemagglutinin (HA) and neuraminidase (NA) provide sterile immunity to infection with the same subtypes. Vaccines targeting viral conserved determinants shared by the influenza A viruses (IAV) offer heterosubtypic immu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Eun Hye, Park, Hae-Jung, Han, Gye-Yeong, Song, Man-Ki, Pereboev, Alexander, Hong, Jeong S., Chang, Jun, Byun, Young-Ho, Seong, Baik Lin, Nguyen, Huan H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136366/
https://ncbi.nlm.nih.gov/pubmed/24920793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00823-14
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