Transcriptional and Posttranscriptional Regulation of Cytokine Gene Expression in HIV-1 Antigen-Specific CD8(+) T Cells That Mediate Virus Inhibition

The ability of CD8(+) T cells to effectively limit HIV-1 replication and block HIV-1 acquisition is determined by the capacity to rapidly respond to HIV-1 antigens. Understanding both the functional properties and regulation of an effective CD8(+) response would enable better evaluation of T cell-di...

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Autores principales: Payne, Tamika L., Blackinton, Jeff, Frisbee, Alyse, Pickeral, Joy, Sawant, Sheetal, Vandergrift, Nathan A., Freel, Stephanie A., Ferrari, Guido, Keene, Jack D., Tomaras, Georgia D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136361/
https://ncbi.nlm.nih.gov/pubmed/24899193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00802-14
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