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Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation

Global mRNA abundance depends on the balance of synthesis and decay of a population of mRNAs. To account for this balance during activation of T cells, we used metabolic labeling to quantify the contributions of RNA transcription and decay over a 4 h time course during activation of leukemia-derived...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Blackinton, Jeff G., Keene, Jack D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705648/
https://ncbi.nlm.nih.gov/pubmed/26490963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1066
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