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Influenza A Virus Hemagglutinin and Neuraminidase Mutually Accelerate Their Apical Targeting through Clustering of Lipid Rafts

In polarized epithelial cells, influenza A virus hemagglutinin (HA) and neuraminidase (NA) are intrinsically associated with lipid rafts and target the apical plasma membrane for viral assembly and budding. Previous studies have indicated that the transmembrane domain (TMD) and cytoplasmic tail (CT)...

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Bibliografiske detaljer
Main Authors: Ohkura, Takashi, Momose, Fumitaka, Ichikawa, Reiko, Takeuchi, Kaoru, Morikawa, Yuko
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136309/
https://ncbi.nlm.nih.gov/pubmed/24965459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00586-14
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