Influenza A Virus Hemagglutinin and Neuraminidase Mutually Accelerate Their Apical Targeting through Clustering of Lipid Rafts

In polarized epithelial cells, influenza A virus hemagglutinin (HA) and neuraminidase (NA) are intrinsically associated with lipid rafts and target the apical plasma membrane for viral assembly and budding. Previous studies have indicated that the transmembrane domain (TMD) and cytoplasmic tail (CT)...

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Hlavní autoři: Ohkura, Takashi, Momose, Fumitaka, Ichikawa, Reiko, Takeuchi, Kaoru, Morikawa, Yuko
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136309/
https://ncbi.nlm.nih.gov/pubmed/24965459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00586-14
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