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Influenza A Virus Hemagglutinin and Neuraminidase Mutually Accelerate Their Apical Targeting through Clustering of Lipid Rafts

In polarized epithelial cells, influenza A virus hemagglutinin (HA) and neuraminidase (NA) are intrinsically associated with lipid rafts and target the apical plasma membrane for viral assembly and budding. Previous studies have indicated that the transmembrane domain (TMD) and cytoplasmic tail (CT)...

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Detalhes bibliográficos
Main Authors: Ohkura, Takashi, Momose, Fumitaka, Ichikawa, Reiko, Takeuchi, Kaoru, Morikawa, Yuko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136309/
https://ncbi.nlm.nih.gov/pubmed/24965459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00586-14
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