Deep Sequencing of HIV-Infected Cells: Insights into Nascent Transcription and Host-Directed Therapy

Polyadenylated mature mRNAs are the focus of standard transcriptome analyses. However, the profiling of nascent transcripts, which often include nonpolyadenylated RNAs, can unveil novel insights into transcriptional regulation. Here, we separately sequenced total RNAs (Total RNAseq) and mRNAs (mRNAs...

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Detalhes bibliográficos
Main Authors: Peng, Xinxia, Sova, Pavel, Green, Richard R., Thomas, Matthew J., Korth, Marcus J., Proll, Sean, Xu, Jiabao, Cheng, Yanbing, Yi, Kang, Chen, Li, Peng, Zhiyu, Wang, Jun, Palermo, Robert E., Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136300/
https://ncbi.nlm.nih.gov/pubmed/24850744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00768-14
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