Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase.

Feline immunodeficiency virus (FIV) encodes the enzyme deoxyuridine-triphosphatase (DU; EC 3.6.1.23) between the coding regions for reverse transcriptase and integrase in the pol gene. Here, we report the in vivo infection of cats with a DU- variant of the PPR strain of FIV and compare its growth pr...

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Autores principales: Lerner, D L, Wagaman, P C, Phillips, T R, Prospero-Garcia, O, Henriksen, S J, Fox, H S, Bloom, F E, Elder, J H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC41363/
https://ncbi.nlm.nih.gov/pubmed/7638216
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