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Quantitative Proteomic Analysis of the Influenza A Virus Nonstructural Proteins NS1 and NS2 during Natural Cell Infection Identifies PACT as an NS1 Target Protein and Antiviral Host Factor

Influenza A virus (IAV) replication depends on the interaction of virus proteins with host factors. The viral nonstructural protein 1 (NS1) is essential in this process by targeting diverse cellular functions, including mRNA splicing and translation, cell survival, and immune defense, in particular...

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Detalhes bibliográficos
Main Authors: Tawaratsumida, Kazuki, Phan, Van, Hrincius, Eike R., High, Anthony A., Webby, Richard, Redecke, Vanessa, Häcker, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136281/
https://ncbi.nlm.nih.gov/pubmed/24899174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00830-14
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