Disease Severity Is Associated with Differential Gene Expression at the Early and Late Phases of Infection in Nonhuman Primates Infected with Different H5N1 Highly Pathogenic Avian Influenza Viruses

Occasional transmission of highly pathogenic avian H5N1 influenza viruses to humans causes severe pneumonia with high mortality. To better understand the mechanisms via which H5N1 viruses induce severe disease in humans, we infected cynomolgus macaques with six different H5N1 strains isolated from h...

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主要な著者: Muramoto, Yukiko, Shoemaker, Jason E., Le, Mai Quynh, Itoh, Yasushi, Tamura, Daisuke, Sakai-Tagawa, Yuko, Imai, Hirotaka, Uraki, Ryuta, Takano, Ryo, Kawakami, Eiryo, Ito, Mutsumi, Okamoto, Kiyoko, Ishigaki, Hirohito, Mimuro, Hitomi, Sasakawa, Chihiro, Matsuoka, Yukiko, Noda, Takeshi, Fukuyama, Satoshi, Ogasawara, Kazumasa, Kitano, Hiroaki, Kawaoka, Yoshihiro
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
Cellular Response to Infection
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136255/
https://ncbi.nlm.nih.gov/pubmed/24899188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00907-14
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