Host Species Restriction of Middle East Respiratory Syndrome Coronavirus through Its Receptor, Dipeptidyl Peptidase 4

Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012. Recently, the MERS-CoV receptor dipeptidyl peptidase 4 (DPP4) was identified and the specific interaction of the receptor-binding domain (RBD) of MERS-CoV spike protein and DPP4 was determined by crystallography. Animal studies...

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Detalhes bibliográficos
Main Authors: van Doremalen, Neeltje, Miazgowicz, Kerri L., Milne-Price, Shauna, Bushmaker, Trenton, Robertson, Shelly, Scott, Dana, Kinne, Joerg, McLellan, Jason S., Zhu, Jiang, Munster, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136254/
https://ncbi.nlm.nih.gov/pubmed/24899185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00676-14
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