Surface Structure Characterization of Aspergillus fumigatus Conidia Mutated in the Melanin Synthesis Pathway and Their Human Cellular Immune Response

In Aspergillus fumigatus, the conidial surface contains dihydroxynaphthalene (DHN)-melanin. Six-clustered gene products have been identified that mediate sequential catalysis of DHN-melanin biosynthesis. Melanin thus produced is known to be a virulence factor, protecting the fungus from the host def...

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Auteurs principaux: Bayry, Jagadeesh, Beaussart, Audrey, Dufrêne, Yves F., Sharma, Meenu, Bansal, Kushagra, Kniemeyer, Olaf, Aimanianda, Vishukumar, Brakhage, Axel A., Kaveri, Srini V., Kwon-Chung, Kyung J., Latgé, Jean-Paul, Beauvais, Anne
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136205/
https://ncbi.nlm.nih.gov/pubmed/24818666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01726-14
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