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Identification of four acidic amino acids that constitute the catalytic center of the RuvC Holliday junction resolvase.

Escherichia coli RuvC protein is a specific endonuclease that resolves Holliday junctions during homologous recombination. Since the endonucleolytic activity of RuvC requires a divalent cation and since 3 or 4 acidic residues constitute the catalytic centers of several nucleases that require a dival...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Saito, A, Iwasaki, H, Ariyoshi, M, Morikawa, K, Shinagawa, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41361/
https://ncbi.nlm.nih.gov/pubmed/7638215
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