Evaluation of SSYA10-001 as a Replication Inhibitor of Severe Acute Respiratory Syndrome, Mouse Hepatitis, and Middle East Respiratory Syndrome Coronaviruses

We have previously shown that SSYA10-001 blocks severe acute respiratory syndrome coronavirus (SARS-CoV) replication by inhibiting SARS-CoV helicase (nsp13). Here, we show that SSYA10-001 also inhibits replication of two other coronaviruses, mouse hepatitis virus (MHV) and Middle Eastern respiratory...

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Autores principales: Adedeji, Adeyemi O., Singh, Kamalendra, Kassim, Ademola, Coleman, Christopher M., Elliott, Ruth, Weiss, Susan R., Frieman, Matthew B., Sarafianos, Stefan G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136041/
https://ncbi.nlm.nih.gov/pubmed/24841268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02994-14
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