Efficacy of Repeated Intravenous Administration of Peramivir against Highly Pathogenic Avian Influenza A (H5N1) Virus in Cynomolgus Macaques

Highly pathogenic avian influenza A (H5N1) viruses cause severe and often fatal disease in humans. We evaluated the efficacy of repeated intravenous dosing of the neuraminidase inhibitor peramivir against highly pathogenic avian influenza virus A/Vietnam/UT3040/2004 (H5N1) infection in cynomolgus ma...

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Bibliographische Detailangaben
Hauptverfasser: Kitano, Mitsutaka, Itoh, Yasushi, Ishigaki, Hirohito, Nakayama, Misako, Ishida, Hideaki, Pham, Van Loi, Arikata, Masahiko, Shichinohe, Shintaro, Tsuchiya, Hideaki, Kitagawa, Naoko, Kobayashi, Masanori, Yoshida, Ryu, Sato, Akihiko, Le, Quynh Mai, Kawaoka, Yoshihiro, Ogasawara, Kazumasa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135987/
https://ncbi.nlm.nih.gov/pubmed/24913156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02817-14
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