Carbapenem-Resistant Klebsiella pneumoniae Strains Exhibit Diversity in Aminoglycoside-Modifying Enzymes, Which Exert Differing Effects on Plazomicin and Other Agents

We measured in vitro activity of plazomicin, a next-generation aminoglycoside, and other aminoglycosides against 50 carbapenem-resistant Klebsiella pneumoniae strains from two centers and correlated the results with the presence of various aminoglycoside-modifying enzymes (AMEs). Ninety-four percent...

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Detalhes bibliográficos
Main Authors: Almaghrabi, Reem, Clancy, Cornelius J., Doi, Yohei, Hao, Binghua, Chen, Liang, Shields, Ryan K., Press, Ellen G., Iovine, Nicole M., Townsend, Bethany M., Wagener, Marilyn M., Kreiswirth, Barry, Nguyen, M. Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135979/
https://ncbi.nlm.nih.gov/pubmed/24867988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00099-14
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