N-Glycolylneuraminic Acid on Human Epithelial Cells Prevents Entry of Influenza A Viruses That Possess N-Glycolylneuraminic Acid Binding Ability

Some animal influenza A viruses (IAVs) bind not only to N-acetylneuraminic acid (Neu5Ac) but also to N-glycolylneuraminic acid (Neu5Gc), which has been discussed as a virus receptor. Human cells cannot synthesize Neu5Gc due to dysfunction of the CMP-Neu5Ac hydroxylase (CMAH) gene, which converts CMP...

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Bibliographische Detailangaben
Hauptverfasser: Takahashi, Tadanobu, Takano, Maiko, Kurebayashi, Yuuki, Masuda, Midori, Kawagishi, Sawako, Takaguchi, Masahiro, Yamanaka, Takashi, Minami, Akira, Otsubo, Tadamune, Ikeda, Kiyoshi, Suzuki, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135951/
https://ncbi.nlm.nih.gov/pubmed/24829344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00716-14
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