Catalytic preference of Salmonella typhimurium LT2 sialidase for N-acetylneuraminic acid residues over N-glycolylneuraminic acid residues()

In a comparison of sialidase activities toward N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc), we found that Salmonella typhimurium LT2 sialidase (STSA) hardly cleaved 4-methylumbelliferyl Neu5Gc (4MU-Neu5Gc). The k(cat)/K(m) value of STSA for 4MU-Neu5Gc was found to be 110...

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Main Authors: Minami, Akira, Ishibashi, Sayaka, Ikeda, Kiyoshi, Ishitsubo, Erika, Hori, Takanori, Tokiwa, Hiroaki, Taguchi, Risa, Ieno, Daisuke, Otsubo, Tadamune, Matsuda, Yukino, Sai, Saki, Inada, Mari, Suzuki, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678298/
https://ncbi.nlm.nih.gov/pubmed/23772399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2013.05.002
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