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Structural Insight into BH3 Domain Binding of Vaccinia Virus Antiapoptotic F1L

Apoptosis is a tightly regulated process that plays a crucial role in the removal of virus-infected cells, a process controlled by both pro- and antiapoptotic members of the Bcl-2 family. The proapoptotic proteins Bak and Bax are regulated by antiapoptotic Bcl-2 proteins and are also activated by a...

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Autors principals: Campbell, Stephanie, Thibault, John, Mehta, Ninad, Colman, Peter M., Barry, Michele, Kvansakul, Marc
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135939/
https://ncbi.nlm.nih.gov/pubmed/24850748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01092-14
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