In Vitro Efficacy of Brincidofovir against Variola Virus

Brincidofovir (CMX001), a lipid conjugate of the acyclic nucleotide phosphonate cidofovir, is under development for smallpox treatment using “the Animal Rule,” established by the FDA in 2002. Brincidofovir reduces mortality caused by orthopoxvirus infection in animal models. Compared to cidofovir, b...

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Autors principals: Olson, Victoria A., Smith, Scott K., Foster, Scott, Li, Yu, Lanier, E. Randall, Gates, Irina, Trost, Lawrence C., Damon, Inger K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135866/
https://ncbi.nlm.nih.gov/pubmed/24957837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02814-14
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