In Vitro Efficacy of Brincidofovir against Variola Virus

Brincidofovir (CMX001), a lipid conjugate of the acyclic nucleotide phosphonate cidofovir, is under development for smallpox treatment using “the Animal Rule,” established by the FDA in 2002. Brincidofovir reduces mortality caused by orthopoxvirus infection in animal models. Compared to cidofovir, b...

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Bibliografske podrobnosti
Main Authors: Olson, Victoria A., Smith, Scott K., Foster, Scott, Li, Yu, Lanier, E. Randall, Gates, Irina, Trost, Lawrence C., Damon, Inger K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135866/
https://ncbi.nlm.nih.gov/pubmed/24957837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02814-14
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