In Vitro Efficacy of Brincidofovir against Variola Virus

Brincidofovir (CMX001), a lipid conjugate of the acyclic nucleotide phosphonate cidofovir, is under development for smallpox treatment using “the Animal Rule,” established by the FDA in 2002. Brincidofovir reduces mortality caused by orthopoxvirus infection in animal models. Compared to cidofovir, b...

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Detalhes bibliográficos
Main Authors: Olson, Victoria A., Smith, Scott K., Foster, Scott, Li, Yu, Lanier, E. Randall, Gates, Irina, Trost, Lawrence C., Damon, Inger K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135866/
https://ncbi.nlm.nih.gov/pubmed/24957837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02814-14
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