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In Vitro Efficacy of Brincidofovir against Variola Virus
Brincidofovir (CMX001), a lipid conjugate of the acyclic nucleotide phosphonate cidofovir, is under development for smallpox treatment using “the Animal Rule,” established by the FDA in 2002. Brincidofovir reduces mortality caused by orthopoxvirus infection in animal models. Compared to cidofovir, b...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135866/ https://ncbi.nlm.nih.gov/pubmed/24957837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02814-14 |
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