Multicenter, Double-Blind, Randomized, Phase II Trial To Assess the Safety and Efficacy of Ceftolozane-Tazobactam plus Metronidazole Compared with Meropenem in Adult Patients with Complicated Intra-Abdominal Infections

Ceftolozane-tazobactam (TOL-TAZ) is a novel antibacterial with activity against Pseudomonas aeruginosa and other common Gram-negative pathogens, including extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae, that are associated with complicated intra-abdominal infections (cIAIs). This...

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Bibliographische Detailangaben
Hauptverfasser: Lucasti, Christopher, Hershberger, Ellie, Miller, Benjamin, Yankelev, Sara, Steenbergen, Judith, Friedland, Ian, Solomkin, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135839/
https://ncbi.nlm.nih.gov/pubmed/24982069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00049-14
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