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Molecular Mechanisms of Substrate Recognition and Specificity of New Delhi Metallo-β-Lactamase

Carbapenems are one of the last lines of defense for Gram-negative pathogens, such as members of the Enterobacteriaceae. Despite the fact that most carbapenems are resistant to extended-spectrum β-lactamase (ESBL), emerging metallo-β-lactamases (MBLs), including New Delhi metallo-β-lactamase 1 (NDM-...

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Detalhes bibliográficos
Main Authors: Chiou, Jiachi, Leung, Thomas Yun-Chung, Chen, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135836/
https://ncbi.nlm.nih.gov/pubmed/24982075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01977-13
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