MHC class I gene expression is negatively regulated by the proto-oncogene, c-jun.

The trans-acting factor AP-1 is a heterodimeric complex composed of c-Jun and c-Fos family proteins which bind and regulate genes containing a TPA responsive enhancer element. Although AP-1 binding sites have been identified within the regulatory region of major histocompatibility complex (MHC) clas...

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Detaylı Bibliyografya
Asıl Yazarlar: Howcroft, T K, Richardson, J C, Singer, D S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1993
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC413582/
https://ncbi.nlm.nih.gov/pubmed/8344255
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