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MHC class I gene expression is negatively regulated by the proto-oncogene, c-jun.

The trans-acting factor AP-1 is a heterodimeric complex composed of c-Jun and c-Fos family proteins which bind and regulate genes containing a TPA responsive enhancer element. Although AP-1 binding sites have been identified within the regulatory region of major histocompatibility complex (MHC) clas...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Howcroft, T K, Richardson, J C, Singer, D S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1993
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413582/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8344255/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05985.x
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