Bactericidal Activity, Absence of Serum Effect, and Time-Kill Kinetics of Ceftazidime-Avibactam against β-Lactamase-Producing Enterobacteriaceae and Pseudomonas aeruginosa

Avibactam, a non-β-lactam β-lactamase inhibitor with activity against extended-spectrum β-lactamases (ESBLs), KPC, AmpC, and some OXA enzymes, extends the antibacterial activity of ceftazidime against most ceftazidime-resistant organisms producing these enzymes. In this study, the bactericidal activ...

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Autori principali: Keepers, Tiffany R., Gomez, Marcela, Celeri, Chris, Nichols, Wright W., Krause, Kevin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135815/
https://ncbi.nlm.nih.gov/pubmed/24957838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02894-14
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