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Chromatinized Protein Kinase C-θ Directly Regulates Inducible Genes in Epithelial to Mesenchymal Transition and Breast Cancer Stem Cells

Epithelial to mesenchymal transition (EMT) is activated during cancer invasion and metastasis, enriches for cancer stem cells (CSCs), and contributes to therapeutic resistance and disease recurrence. Signal transduction kinases play a pivotal role as chromatin-anchored proteins in eukaryotes. Here w...

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Detalhes bibliográficos
Main Authors: Zafar, Anjum, Wu, Fan, Hardy, Kristine, Li, Jasmine, Tu, Wen Juan, McCuaig, Robert, Harris, Janelle, Khanna, Kum Kum, Attema, Joanne, Gregory, Philip A., Goodall, Gregory J., Harrington, Kirsti, Dahlstrom, Jane E., Boulding, Tara, Madden, Rebecca, Tan, Abel, Milburn, Peter J., Rao, Sudha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135602/
https://ncbi.nlm.nih.gov/pubmed/24891615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01693-13
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