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Overexpression of Epigen during Embryonic Development Induces Reversible, Epidermal Growth Factor Receptor-Dependent Sebaceous Gland Hyperplasia

The epidermal growth factor receptor (EGFR) system is a key regulator of epithelial development and homeostasis. Its functions in the sebaceous gland (SG), however, remain poorly characterized. In this study, using a transgenic mouse line with tissue-specific and inducible expression of the EGFR lig...

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Autors principals: Dahlhoff, Maik, Frances, Daniela, Kloepper, Jennifer E., Paus, Ralf, Schäfer, Matthias, Niemann, Catherin, Schneider, Marlon R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135600/
https://ncbi.nlm.nih.gov/pubmed/24891618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00302-14
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