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PLIN2, the major perilipin regulated during sebocyte differentiation, controls sebaceous lipid accumulation in vitro and sebaceous gland size in vivo

BACKGROUND: Lipid synthesis and storage are accomplished by lipid droplets (LDs). The perilipin family of LD-associated proteins, comprising 5 members (PLIN1-PLIN5), has been well characterized in adipocytes but not in sebocytes, epithelial cells in which LD formation is a key feature of the cellula...

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Detalhes bibliográficos
Main Authors: Dahlhoff, Maik, Camera, Emanuela, Picardo, Mauro, Zouboulis, Christos C., Chan, Lawrence, Chang, Benny Hung-Junn, Schneider, Marlon R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998206/
https://ncbi.nlm.nih.gov/pubmed/23688400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.05.016
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