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Direct Interaction between the WD40 Repeat Protein WDR-23 and SKN-1/Nrf Inhibits Binding to Target DNA

SKN-1/Nrf transcription factors activate cytoprotective genes in response to reactive small molecules and strongly influence stress resistance, longevity, and development. The molecular mechanisms of SKN-1/Nrf regulation are poorly defined. We previously identified the WD40 repeat protein WDR-23 as...

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Hlavní autoři: Leung, Chi K., Hasegawa, Koichi, Wang, Ying, Deonarine, Andrew, Tang, Lanlan, Miwa, Johji, Choe, Keith P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135592/
https://ncbi.nlm.nih.gov/pubmed/24912676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00114-14
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