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CARM1 is Required in Embryonic Stem Cells to Maintain Pluripotency and Resist Differentiation
Histone H3 methylation at R17 and R26 recently emerged as a novel epigenetic mechanism regulating pluripotency in mouse embryos. Blastomeres of four-cell embryos with high H3 methylation at these sites show unrestricted potential, whereas those with lower levels cannot support development when aggre...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135545/ https://ncbi.nlm.nih.gov/pubmed/19544422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.131 |
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