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Solid-Phase Chemoenzymatic Synthesis of C-Sialosides
The chemoenzymatic regioselective acylation of Neu5Ac followed by SmI(2)-mediated C-glycosylation on a solid support is described for five C-glycosides. This method should facilitate the construction of combinatorial libraries of inhibitors of neuraminidase activity and hemagglutinin interaction as...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135478/ https://ncbi.nlm.nih.gov/pubmed/15387620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo0491298 |
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