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Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis

DNA-damage response and repair are crucial to maintain genetic stability, and are consequently considered central to aging and longevity. Here, we investigate whether this pathway overall associates to longevity, and whether specific sub-processes are more strongly associated with longevity than oth...

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Sonraí Bibleagrafaíochta
Main Authors: Debrabant, Birgit, Soerensen, Mette, Flachsbart, Friederike, Dato, Serena, Mengel-From, Jonas, Stevnsner, Tinna, Bohr, Vilhelm A, Kruse, Torben A, Schreiber, Stefan, Nebel, Almut, Christensen, Kaare, Tan, Qihua, Christiansen, Lene
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135411/
https://ncbi.nlm.nih.gov/pubmed/24518833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.299
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