Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis

DNA-damage response and repair are crucial to maintain genetic stability, and are consequently considered central to aging and longevity. Here, we investigate whether this pathway overall associates to longevity, and whether specific sub-processes are more strongly associated with longevity than oth...

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Autors principals: Debrabant, Birgit, Soerensen, Mette, Flachsbart, Friederike, Dato, Serena, Mengel-From, Jonas, Stevnsner, Tinna, Bohr, Vilhelm A, Kruse, Torben A, Schreiber, Stefan, Nebel, Almut, Christensen, Kaare, Tan, Qihua, Christiansen, Lene
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135411/
https://ncbi.nlm.nih.gov/pubmed/24518833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.299
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