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The Cdc48–Vms1 complex maintains 26S proteasome architecture
The 26S proteasome is responsible for most regulated protein turnover and for the degradation of aberrant proteins in eukaryotes. The assembly of this ~2.5 MDa multicatalytic protease requires several dedicated chaperones and, once assembled, substrate selectivity is mediated by ubiquitin conjugatio...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135392/ https://ncbi.nlm.nih.gov/pubmed/24351022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131161 |
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