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Single-molecule detection of a guanine(C8) - thymine(N3) cross-link using ion channel recording()

The capability to identify and sequence DNA damage within the context of the genome is an important goal for medical diagnostics. However, currently available methods are not suitable for this purpose. Ion channel nanopore analysis shows promise as a potential single-molecule method to sequence geno...

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Autors principals: Wolna, Anna H., Fleming, Aaron M., Burrows, Cynthia J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135377/
https://ncbi.nlm.nih.gov/pubmed/25147426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/poc.3240
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