NEK9-dependent proliferation of cancer cells lacking functional p53

Dysfunction of the p53 network is a major cause of cancer development, and selective elimination of p53-inactivated cancer cells therefore represents an ideal therapeutic strategy. In this study, we performed a microRNA target screen that identified NEK9 (NIMA-related kinase 9) as a crucial regulato...

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Bibliographische Detailangaben
Hauptverfasser: Kurioka, Daisuke, Takeshita, Fumitaka, Tsuta, Koji, Sakamoto, Hiromi, Watanabe, Shun-ichi, Matsumoto, Kenji, Watanabe, Masatoshi, Nakagama, Hitoshi, Ochiya, Takahiro, Yokota, Jun, Kohno, Takashi, Tsuchiya, Naoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135330/
https://ncbi.nlm.nih.gov/pubmed/25131192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06111
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