Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3OH-kinase and src-related tyrosine kinase(s) in human myeloid derived cells.

The signalling pathways used by the GM-CSF receptor are currently unknown. Here we show that in human myeloid derived cells GM-CSF can stimulate; (i) the accumulation of PtdIns(3,4,5)P3; (ii) increases in p53/p56lyn and p62c-yes directed protein tyrosine kinase activities in anti-lyn and anti-c-yes...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Corey, S, Eguinoa, A, Puyana-Theall, K, Bolen, J B, Cantley, L, Mollinedo, F, Jackson, T R, Hawkins, P T, Stephens, L R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1993
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC413516/
https://ncbi.nlm.nih.gov/pubmed/8392933
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