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Synthesis, Characterization and In Vitro Anticancer Activity of C-5 Curcumin Analogues with Potential to Inhibit TNF-α-Induced NF-κB Activation

In a search of new compounds active against cancer, synthesis of a series of C-5 curcumin analogues was carried out. The new compounds demonstrated good cytotoxicity against chronic myeloid leukemia (KBM5) and colon cancer (HCT116) cell lines. Further, these compounds were found to have better poten...

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Bibliografske podrobnosti
Main Authors: Anthwal, Amit, Thakur, Bandana K., Rawat, M. S. M., Rawat, D. S., Tyagi, Amit K., Aggarwal, Bharat B.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135142/
https://ncbi.nlm.nih.gov/pubmed/25157362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/524161
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