Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src.

The protein tyrosine kinase c-Src is negatively regulated by phosphorylation of Tyr527 in its carboxy-terminal tail. A kinase that phosphorylates Tyr527, called Csk, has recently been identified. We expressed c-Src in yeast to test the role of the SH2 and SH3 domains of Src in the negative regulatio...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Superti-Furga, G, Fumagalli, S, Koegl, M, Courtneidge, S A, Draetta, G
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7687537/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05923.x
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