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Zfp318 regulates IgD expression by abrogating transcription termination within the Ighm/Ighd locus

The protein Zfp318 is expressed during the transition of naïve B cells from an immature to mature state. To evaluate its role in mature B cell functions, a conditional gene deficiency in Zfp318 was created and deleted in bone marrow lineages via Vav-Cre. B cell development was minimally altered in t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pioli, Peter D., Debnath, Irina, Weis, Janis J., Weis, John H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135021/
https://ncbi.nlm.nih.gov/pubmed/25057009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401275
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