Success of measles virotherapy in ATL depends on type I interferon secretion and responsiveness

Adult T cell leukemia/lymphoma (ATL) is a highly aggressive CD4+/CD25+ T-cell malignancy caused by human T cell lymphotropic virus type 1 (HTLV-1). Previous studies in the MET-1 cell /NOD/SCID mouse model of ATL demonstrated that MET-1 cells are very susceptible to measles virus (MV) oncolytic thera...

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Detalhes bibliográficos
Main Authors: Parrula, Cecilia, Fernandez, Soledad A., Landes, Kristina, Huey, Devra, Lairmore, Michael, Niewiesk, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134976/
https://ncbi.nlm.nih.gov/pubmed/24911240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2014.05.025
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