Inhibition of Major Histocompatibility Complex Class II-Dependent Antigen Presentation by Neutralization of Gamma Interferon Leads to Breakdown of Resistance against Measles Virus-Induced Encephalitis

BALB/c mice are resistant to measles virus (MV)-induced encephalitis due to their strong MV-specific CD4(+) T-cell response. Resistance is broken by neutralization of gamma interferon with monoclonal antibodies, indicating an important role for this pleiotropic cytokine. Here, we demonstrate that mo...

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Detalhes bibliográficos
Main Authors: Weidinger, Gerald, Henning, Golo, ter Meulen, Volker, Niewiesk, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114099/
https://ncbi.nlm.nih.gov/pubmed/11238832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3059-3065.2001
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