Essential nucleotide sequences and secondary structure elements of the hairpin ribozyme.

In vitro selection experiments have been used to isolate active variants of the 50 nt hairpin catalytic RNA motif following randomization of individual ribozyme domains and intensive mutagenesis of the ribozyme-substrate complex. Active and inactive variants were characterized by sequencing, analysi...

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Bibliographic Details
Main Authors: Berzal-Herranz, A, Joseph, S, Chowrira, B M, Butcher, S E, Burke, J M
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC413496/
https://ncbi.nlm.nih.gov/pubmed/8508779
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