Essential nucleotide sequences and secondary structure elements of the hairpin ribozyme.

In vitro selection experiments have been used to isolate active variants of the 50 nt hairpin catalytic RNA motif following randomization of individual ribozyme domains and intensive mutagenesis of the ribozyme-substrate complex. Active and inactive variants were characterized by sequencing, analysi...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Berzal-Herranz, A, Joseph, S, Chowrira, B M, Butcher, S E, Burke, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413496/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8508779/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05912.x
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