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PBX1 is a Favorable Prognostic Biomarker as it Modulates 13-cis Retinoic Acid-mediated Differentiation in Neuroblastoma

PURPOSE: Neuroblastoma is an embryonic childhood cancer with high mortality. 13-cis retinoic acid (13-cisRA) improves survival for some patients, but many recur, suggesting clinical resistance. The mechanism of resistance, and the normal differentiation pathway, are poorly understood. Three-Amino-ac...

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Main Authors: Shah, Nilay, Wang, Jianjun, Selich-Anderson, Julia, Graham, Garrett, Siddiqui, Hasan, Li, Xin, Khan, Javed, Toretsky, Jeffrey
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134768/
https://ncbi.nlm.nih.gov/pubmed/24947929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1486
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