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Insulin in the Brain: There and Back Again

Insulin performs unique functions within the CNS. Produced nearly exclusively by the pancreas, insulin crosses the blood-brain barrier (BBB) using a saturable transporter, affecting feeding and cognition through CNS mechanisms largely independent of glucose utilization. Whereas peripheral insulin ac...

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Bibliografiske detaljer
Main Authors: Banks, William A., Owen, Joshua B., Erickson, Michelle A
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134675/
https://ncbi.nlm.nih.gov/pubmed/22820012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2012.07.006
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