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Insulin in the Brain: There and Back Again
Insulin performs unique functions within the CNS. Produced nearly exclusively by the pancreas, insulin crosses the blood-brain barrier (BBB) using a saturable transporter, affecting feeding and cognition through CNS mechanisms largely independent of glucose utilization. Whereas peripheral insulin ac...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134675/ https://ncbi.nlm.nih.gov/pubmed/22820012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2012.07.006 |
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