Stem loop recognition by DDX17 facilitates miRNA processing and antiviral defense

DEAD-box helicases play essential roles in RNA metabolism across species, but emerging data suggest that they have additional functions in immunity. Through RNAi screening we identify an evolutionarily conserved and interferon-independent role for the DEAD-box helicase DDX17 in restricting Rift Vall...

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Détails bibliographiques
Auteurs principaux: Moy, Ryan H., Cole, Brian S., Yasunaga, Ari, Gold, Beth, Shankarling, Ganesh, Varble, Andrew, Molleston, Jerome M., tenOever, Benjamin R., Lynch, Kristen W., Cherry, Sara
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134512/
https://ncbi.nlm.nih.gov/pubmed/25126784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.023
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