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Stem loop recognition by DDX17 facilitates miRNA processing and antiviral defense

DEAD-box helicases play essential roles in RNA metabolism across species, but emerging data suggest that they have additional functions in immunity. Through RNAi screening we identify an evolutionarily conserved and interferon-independent role for the DEAD-box helicase DDX17 in restricting Rift Vall...

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Detalhes bibliográficos
Main Authors: Moy, Ryan H., Cole, Brian S., Yasunaga, Ari, Gold, Beth, Shankarling, Ganesh, Varble, Andrew, Molleston, Jerome M., tenOever, Benjamin R., Lynch, Kristen W., Cherry, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134512/
https://ncbi.nlm.nih.gov/pubmed/25126784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.023
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