Stem loop recognition by DDX17 facilitates miRNA processing and antiviral defense

DEAD-box helicases play essential roles in RNA metabolism across species, but emerging data suggest that they have additional functions in immunity. Through RNAi screening we identify an evolutionarily conserved and interferon-independent role for the DEAD-box helicase DDX17 in restricting Rift Vall...

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Autori principali: Moy, Ryan H., Cole, Brian S., Yasunaga, Ari, Gold, Beth, Shankarling, Ganesh, Varble, Andrew, Molleston, Jerome M., tenOever, Benjamin R., Lynch, Kristen W., Cherry, Sara
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134512/
https://ncbi.nlm.nih.gov/pubmed/25126784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.023
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