Src, a potential target for overcoming trastuzumab resistance in HER2-positive breast carcinoma

BACKGROUND: Src is a non-receptor tyrosine kinase involved in signalling and crosstalk between growth-promoting pathways. We aim to investigate the relationship of active Src in response to trastuzumab of HER2-positive breast carcinomas. METHODS: We selected 278 HER2-positive breast cancer patients...

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Detalhes bibliográficos
Main Authors: Peiró, G, Ortiz-Martínez, F, Gallardo, A, Pérez-Balaguer, A, Sánchez-Payá, J, Ponce, J J, Tibau, A, López-Vilaro, L, Escuin, D, Adrover, E, Barnadas, A, Lerma, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134494/
https://ncbi.nlm.nih.gov/pubmed/24937674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.327
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