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Improved Statistical Signal Detection in Pharmacovigilance by Combining Multiple Strength-of-Evidence Aspects in vigiRank: Retrospective Evaluation against Emerging Safety Signals

BACKGROUND: Detection of unknown risks with marketed medicines is key to securing the optimal care of individual patients and to reducing the societal burden from adverse drug reactions. Large collections of individual case reports remain the primary source of information and require effective analy...

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Hlavní autoři: Caster, Ola, Juhlin, Kristina, Watson, Sarah, Norén, G. Niklas
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134478/
https://ncbi.nlm.nih.gov/pubmed/25052742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-014-0204-5
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